Effect of high-dose intravenous vitamin C on inflammation in cancer patients

Effect of high-dose intravenous vitamin C on inflammation in cancer patients

Abstract
Background: An inflammatory component is present in the microenvironment of most neoplastic tissues.
Inflammation and elevated C-reactive protein (CRP) are associated with poor prognosis and decreased survival in
many types of cancer.
Vitamin C has been suggested as having both a preventative and therapeutic role in a number of pathologies
when administered at much higher-than-recommended dietary allowance levels.
Since in vitro studies demonstrated inhibition of pro-inflammatory pathways by millimolar concentrations of
vitamin C, we decided to analyze the effects of high dose IVC therapy in suppression of inflammation in cancer
patients.

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